Isotopically Labeled Compounds
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Revvity Health Sciences Inc SCH 23390, [N-Methyl-3H]-, 1mCi (37MBq)
SCH 23390, [N-Methyl-3H]-, 1mCi (37MBq)
Cayman Chemical Imidacloprid-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 1015855-75-0, 1 mg
An internal standard for the quantification of imidacloprid by GC- or LC-MS
Medchemexpress LLC Bumetanide-d5 | 1216739-35-3 | 99.8% | 369.45 | 5 MG
Bumetanide-d5 is a deuterium-labeled Bumetanide. It functions as a selective Na+-K+-Cl- (NKCC1) inhibitor and weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively. This compound is suitable for use as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled Bumetanide
- Selective Na+-K+-Cl- (NKCC1) inhibitor
- Weakly inhibits NKCC2
- Functions as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC Bisphenol A-d16 | 96210-87-6 | 99.9% | 244.38 | 100 MG
Bisphenol A-d16 is the deuterium labeled Bisphenol A, a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. It is often classified as an endocrine-disrupting compound (EDC) and is associated with various diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductive disorders.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Citrulline-d4 | 1217474-00-4 | 179.21 | 1 MG
L-Citrulline-d4 is a deuterium labeled form of L-Citrulline, an amino acid derived from ornithine in various metabolic pathways. It serves as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, is used for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitative analysis.
- Functions as an internal standard for analytical methods.
- Suitable for NMR, GC-MS, or LC-MS applications.
- Can affect pharmacokinetic and metabolic profiles.
Medchemexpress LLC Deoxycholic acid | 83-44-3 | 392.57 | 1 G
Deoxycholic acid, also known as cholanoic acid, is a bile acid produced as a by-product of intestinal metabolism. It acts by activating the G protein-coupled bile acid receptor TGR5. This product is intended for research use only.
- By-product of intestinal metabolism
- Activates G protein-coupled bile acid receptor TGR5
- Solid appearance, white to off-white
- High purity (99.94%)
- For research use only
Medchemexpress LLC Mequinol-d4 | 126840-02-6 | 98.9% | 128.16 | 5 MG
Mequinol-d4 is a laboratory chemical primarily used for research. It is presented as a solid and is stable under recommended storage conditions. This substance is not classified as hazardous and is intended for experienced personnel in appropriately equipped facilities.
- Used as a laboratory chemical
- Not classified as a hazardous substance
- Stable under recommended storage conditions
- Available as a solid
- Recommended storage for powder: -20°C for 3 years
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
- High purity (98.9%)
Medchemexpress LLC L-Hydroxyproline-d3 | 1356016-86-8 | 99.9% | 134.15 | 5 MG
L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Nifedipine-d6 | 1188266-14-9 | >98% | 5 MG
Nifedipine-d6 (BAY-a-1040-d6) is deuterium labeled nifedipine, which is a potent calcium channel blocker. It is intended for research use only.
- Deuterium labeled nifedipine
- Potent calcium channel blocker
- Intended for research use only
Medchemexpress LLC Estrone-d2-1 | 56588-58-0 | 99.8% | 1 MG
Estrone-d2-1 is a deuterium-labeled form of Estrone (E1), a natural estrogenic hormone produced in various tissues like adipose tissue. It is formed through the aromatization of androstenedione in fat cells. This product is for research use only.
- Stable heavy isotopes incorporated into drug molecules for use as tracers.
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- High purity: 99.75%.
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 5 MG
Adenosine-d13 is a deuterium-labeled form of Adenosine, an endogenous autacoid crucial for various cellular processes. It interacts with G protein-coupled receptors (A1, A2A, A2B, and A3) and plays a role in neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Used as a tracer
- Can serve as an internal standard for quantitative analysis
- Suitable for analysis techniques such as NMR, GC-MS, or LC-MS
Medchemexpress LLC Nicotinamide-d4 | 347841-88-7 | 99.9% | 1 MG
Nicotinamide-d4 is the deuterium labeled Nicotinamide, a form of vitamin B3 essential for cell physiology through NAD+ redox homeostasis. It serves as a substrate for enzymes catalyzing non-redox reactions and is an inhibitor of SIRT1. This product is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Octopamine-d4 hydrochloride | 1219803-62-9 | 98.0% | 1 MG
Octopamine-d4 hydrochloride is a deuterium-labeled form of Octopamine hydrochloride. It acts as a neurohormone, neuromodulator, and neurotransmitter in invertebrates, stimulating alpha2-adrenoceptors. It has been observed to increase glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 2'-Deoxyuridine-13C,15N2 | 369656-76-8 | 98.1% | 1 MG
2'-Deoxyuridine-13C,15N2 is the 13C and 15N labeled 2'-Deoxyuridine, a compound that can increase chromosome breakage and decrease thymidylate synthetase activity. It is also known as a precursor in the synthesis of Edoxudine.
- Can increase chromosome breakage.
- Results in decreased thymidylate synthetase activity.
- Precursor in the synthesis of Edoxudine.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Ethanol-D6 (<6% D2O) | 1516-08-1 | MFCD00051020 | 5 x 1 g
Ethanol-D6 (<6% D2O) | Purity: 99.5% | Mol Wt: 52.11 | 1516-08-1 | MFCD00051020 | 5 x 1 g